Prof. Dr. med. H. G. Bohnet
Unabhängiger Konsiliarius für gyn. Endokrinologie
Vita Prof. Dr. med. H. G. Bohnet:
Geboren 1944 in Schmiegel Kr. Kosten/Warthe
- 1964 – Humanistisches Abitur in Urach
- 1966 – Pharmaziestudium und Vorklinisches Studium der Medizin
- 1968 – Klinisches Studium der Medizin und Grundstudium der Soziologie an der Universität Erlangen/Nürnberg
- 1972 – Staatsexamen der Medizin und Abschluß des Soziologiestudiums (dem Vordiplom entsprechend), Promotion zum Doktor der Medizin an der Universität Erlangen /Nürnberg (Thema: „Der Einfluss von Konfession und Religiosität auf das Verhalten gynäkologischer Patientinnen“)
- 1973 – Medizinalassistent am Institut für Innere Medizin der Universität Erlangen/Nürnberg und am Allgemein-Chirurgischen Krankenhaus der Stadt Bopfingen Kr. Aalen, gynäkologische Facharztausbildung am Department für Frauenheilkunde der Universität Ulm
- 1975 – Stipendiat der Deutschen Forschungsgemeinschaft am Department für Physiologie (Direktor: Prof. Dr. Henry G. Friesen) der Universität von Manitoba, Winnipeg/Kanada,
Tätigkeitsfeld: Radioimmunoassays, Radiorezeptorassays für Laktogene, Gonadotropine und Wachstumshormone; tierphysiologische Studien über Reproduktion und Laktation unter besonderer Berücksichtigung von Proteo- und Steroidhormonrezeptoren; Bestimmung von Rezeptoren beim menschlichen- und tier-experimentellen Mammakarzinom - 1976 – Facharztweiterbildung für Gynäkologie am Department für Frauenheilkunde der Universität Ulm und an der Frauenklinik der Universität Münster
- 1977 – Leiter des DFG-Projektes „Steroidfeedback auf die Gonadotropinsekretion beim weiblichen Hypogonadismus und dessen Abhängigkeit vom Prolaktin“
- 1978 – Anerkennung als Arzt für Frauenheilkunde und Geburtshilfe
- 1979 – Habilitation für das Fach Frauenheilkunde und Geburtshilfe (Habilitationsschrift: „Prolaktin und weibliche Fortpflanzung“)
- 1981 – Niederlassung als Frauenarzt, Leiter der Abteilung Reproduktionsmedizin und In-vitro-Fertilisation am Institut für Hormon und Fortpflanzungsstörungen in Hamburg
- 1985 – Geburt des 1. IVF-Babys in Hamburg (4. in Deutschland)
- 1986 – Visiting Professor am Department für Physiologie der Universität von Manitoba
- 1989 – Winnipeg/Kanada, jeweils drei Monate
- 1992 – Gründungsmitglied der Gemeinschaftspraxis BKS, gynäkologische Endokrinologie und Reproduktionsmedizin
- 1996 – Anerkennung der Fakultativen Weiterbildung in Gynäkologischer Endokrinologie und Reproduktionsmedizin durch die Ärztekammer Hamburg
Publikationen
Control of prolactin secretion in man. pp. 257-81. In: Labrie F, Et Al., Ed. Hypothalamus and Endocrine Functions.
New York, Plenum Press, 1976. W1 CU82M V.3 1976.
Changes in progesterone and estrogen receptors in the rat uterus during the estrous cycle and the puerperium. pp. 245-59. In: McGuire WL, Et Al., Ed. Progesterone Receptors in Normal and Neoplastic Tissues.
New York, Raven Press, 1977. W1 PR667M V.4 1977.
LH-releasing hormone in diagnosis and treatment of hypothalamic amenorrhea. pp. 110-8. In: Da Paz AC, Et Al., Ed. Recent Advances in Human Reproduction.
Amsterdam, Excerpta Medica, 1976. W3 EX89 No.370 1974.
Attempts for standardization of the LH-RH tests. pp. 273-4. In: Franchimont P, Ed. Some Aspects of Hypothalamic Regulation of Endocrine Functions.
Stuttgart, Schattauer, 1975. WL 312 S989s 1973.
Human pituitary gonadotropin index. I. Standardized LRH test criteria for evaluation of functional amenorrhea.
J Clin Endocrinol Metab. 1975 Jun; 40(6):959-69.
TRH stimulation as an attempt at demonstration of the induction and involution of prolactin-secreting pituitary cells in pregnancy and puerperium and in pathological hyperprolactinemia. Endokrinologie. 1975 Nov; 66(2):173-83.
The pulsatile LH fluctuation (spiking) dependent on the circulating prolactin. Studies during physiological (puerperium), functional pathological and TRH induced hyperprolactinemia.
Endokrinologie. 1975 Nov; 66(2):158-72.
LRH and clomiphene tests before and after chronic LRH therapy
Arch Gynakol. 1975 Nov 18; 219(1-4):591-2.
Influence of prolactin concentration on the tonic LH release (spiking)
Arch Gynakol. 1975 Nov 18; 219(1-4):592-3.
Human pituitary gonadotropin index. Statistical evaluation of 413 LRH tests in normal and amenorrhoic females with special reference to plasma estradiol
Arch Gynakol. 1975 Nov 18; 219(1-4):587-9.
Induction of lactogenic receptors. II. Studies on the liver of hypophysectomized male rats and on rats bearing a growth hormone secreting tumor.
Endocr Res Commun. 1976; 3(3-4):199-208.
Lack of a direct effect of homocysteic acid on growth hormone and prolactin receptors.
Endokrinologie. 1976; 68(3):355-8.
Induction of lactogenic receptors. I. In the liver of hypophysectomized female rats.
Endocr Res Commun. 1976; 3(3-4):187-98.
Control of prolactin secretion in man.
Curr Top Mol Endocrinol. 1976; 3:257-81.
Human pituitary gonadotrophin index. II LHRH test and clomiphene response before and after LHRH stimulation.
Clin Endocrinol (Oxf). 1976 Jan; 5(1):25-36.
Hyperprolactinemic anovulatory syndrome.
J Clin Endocrinol Metab. 1976 Jan; 42(1):132-43.
Age and sex differences in prolactin response to phenothiazines in rats.
Biol Reprod. 1976 Sep; 15(2):168-72.
Prolactin binding sites in the male rat liver following castration. Endocrinology.
1976 Oct; 99(4):1017-22.
Effect of prolactin and growth hormone on prolactin and LH receptors in the dwarf mouse.
J Reprod Fertil. 1976 Nov; 48(2):307-11.
Localization of prolactin binding in prostate and testis: The role of serum prolactin concentration on the testicular LH receptor.
Acta Endocrinol (Copenh). 1977 Feb; 84(2):402-9.
Simplified methods for the computation of total release of plasma gonadotropins in the LH-RH test (proceedings)
Arch Gynakol. 1977 Jul 29; 224(1-4):529-31.
Functional diagnosis of the female reproductive system using the LRH-, gestagen-, and Dyneric-tests (proceedings)
Arch Gynakol. 1977 Jul 29; 224(1-4):416.
Prolactin and estrogen binding sites in the mammary gland of the lactating and non-lactating rat. Endocrinology.
1977 Oct; 101(4):1111-21.
Prolactin oversuppression. Arch Gynakol.
1977 Oct 28; 223(3):173-8.
Short luteal phase and prolactin.
Int J Fertil. 1978; 23(3):213-8.
In vivo effects of antisera to prolactin receptors in female rats. Endocrinology.
1978 Jun; 102(6):1657-61.
Effects of cimetidine on prolactin, LH, and sex steroid secretion in male and female volunteers.
Acta Endocrinol (Copenh). 1978 Jul; 88(3):428-34.
Effects of synthetic gestagens on serum prolactin and growth hormone secretion in amenorrheic patients.
Arch Gynecol. 1978 Nov 30; 226(3):233-40.
Effect of ovine prolactin on serum somatomedin bioactivity in hypophysectomized female rats.
Can J Physiol Pharmacol. 1978 Dec; 56(6):984-7.
Gonadotrophin release during chronic administration of D-ser (TBU)6 LH- RH-EA in functional amenorrhoea.
Acta Endocrinol (Copenh). 1978 Dec; 89(4):625-31.
Gonadoblastoma and overgrowing dysgerminoma in Turner mosaicism
Arch Gynecol. 1979 Mar 28; 227(1):47-54. Notes: (author's transl)
Suppression of prolactin secretion by lisuride throughout the menstrual cycle and in hyperprolactinaemic menstrual disorders.
Acta Endocrinol (Copenh). 1979 Sep; 92(1):8-19.
Prolactin: assessment of its role in the human female.
Horm Metab Res. 1979 Oct; 11(10):533-46.
Determination and properties of proteohormone receptors in malignant gynecological tumors with special reference to lactogen receptors in human breast cancer.
Arch Gynecol. 1980; 229(4):333-44.
LH-RH therapy in functional amenorrhea based on clinical subclassification.
Int J Fertil. 1980; 25(3):222-33.
Gonadotropin release after administration of LH-RH during early follicular phase.
Int J Fertil. 1980; 25(2):100-5.
Diagnosis and therapy of amenorrhea (author's transl). MMW Munch Med Wochenschr.
1980 Jun 27; 122(26):957-60.
Modulation of pituitary LH and prolactin pools in amenorrheic women. I. Effects of high dose estrogen or gestagen treatment.
Horm Metab Res. 1980 Aug; 12(8):390-6.
Modulation of pituitary LH and prolactin pools in amenorrheic women. II. Effects of low dose estrogen treatment.
Horm Metab Res. 1980 Sep; 12(9):459-64.
Epimestrol in treatment of inadequate luteal progesterone secretion.
Fertil Steril. 1980 Oct; 34(4):346-50.
Epimestrol in the treatment of normoprolactinemic corpus-lutem deficiency (author's transl)
Geburtshilfe Frauenheilkd. 1980 Oct; 40(10):926-32.
Luteal insufficiency as a prolactin-related disorder of the menstrual cycle
Fortschr Med. 1980 Nov 6; 98(41):1618-23.
Endocrine therapy only in hormone-receptor-positive breast neoplasms.
Med Klin. 1980 Nov 7; 75(23):818-22.
Hyperprolactinemic ovarian insufficiency.
Gynakologe. 1981 Jun; 14(2):104-18.
Domperidone stimulated prolactin secretion in normal male and female volunteers.
Endokrinologie. 1981 Jul; 77(3):363-6.
Changes of prolactin secretion following long-term danazol application.
Fertil Steril. 1981 Dec; 36(6):725-8.
Intermittent stimulation with LH-RH in postmenopausal hypergonadotropism.
Horm Metab Res. 1981 Dec; 13(12):696-9.
Subclinical hypothyroidism and infertility.
Lancet. 1981 Dec 5; 2(8258):1278.
Normoprolactinemia in anovulatory cycles.
Fertil Steril. 1982 Sep; 38(3):392.
Phorbol esters inhibit LH stimulated steroidogenesis by mouse Leydig cells in vitro.
Biochem Biophys Res Commun. 1984 Mar 30; 119(3):1062-7.
Diagnostic value of the prolactin stimulation test in infertile women with galactorrhea
Fortschr Med. 1984 Apr 12; 102(14):394-6.
Preliminary report about a modified gonadotropin (human menopausal gonadotropin/human chorionic gonadotropin) treatment in infertile patients with premature luteinization.
Fertil Steril. 1984 May; 41(5):714-8.
Pollutants in human follicular fluid.
Fertil Steril. 1984 Jul; 42(1):146-8.
Oxytocin and vasopressin have no effect on progesterone production and cyclic AMP accumulation by rat luteal cells in vitro.
J Reprod Fertil. 1984 Sep; 72(1):137-41.
Biocides in human follicular fluid
Ann N Y Acad Sci. 1985; 442:240-50.
Prolactin concentrations in follicular fluid following ovarian hyperstimulation for in vitro fertilization.
Horm Res. 1985; 22(3):189-95.
Prolactin and sex steroid concentrations in follicular fluids after different ovarian stimulation methods in IVF patients.
Ann N Y Acad Sci. 1985; 442:227-35.
Prolactin secretion during pregnancy and puerperium: response to metoclopramide and interactions with placental hormones.
Obstet Gynecol. 1985 Jun; 65(6):789-92.
Unexplained infertility and its treatment with intermittent GnRH application.
J Steroid Biochem. 1985 Nov; 23(5B):863-5.
Treatment of hyperprolactinemic amenorrhea with Metergoline.
Obstet Gynecol. 1986 Feb; 67(2):249-52.
Phorbol ester stimulates progesterone production by isolated bovine luteal cells.
Endocrinology. 1986 Feb; 118(2):743-9.
Different hormonal patterns in human menopausal gonadotropin-treated, clomiphene citrate-treated, and untreated conception cycles.
Fertil Steril. 1986 Apr; 45(4):469-74.
Testosterone production by mouse Leydig cells is stimulated in vitro by atrial natriuretic factor.
FEBS Lett. 1986 Jun 23; 202(1):111-6.
Preparation and properties of human chorionic gonadotropin antagonist for biological studies: antifertility effects in the female rat.
Acta Endocrinol (Copenh). 1986 Aug; 112(4):586-94.
New aspects of oestrogen/gestagen-induced growth and endocrine changes in individuals with Turner syndrome.
Eur J Pediatr. 1986 Sep; 145(4):275-9.
Human placental lactogen and unconjugated estriol concentrations in twin pregnancy: monitoring of fetal development in intrauterine growth retardation and single intrauterine fetal death.
Am J Obstet Gynecol. 1986 Nov; 155(5):1027-31.
A pregnancy without detectable human placental lactogen (hPL)
Zentralbl Gynakol. 1987; 109(2):130-3.
Evaluation of basal hormone levels in hirsute women.
Exp Clin Endocrinol. 1987 Mar; 89(1):31-8.
Prolactin stimulation tests: different response patterns after bromocriptine, lisuride, and metergoline treatment of puerperal women.
Obstet Gynecol. 1988 Jan; 71(1):53-5.
A human B-lymphoblastoid cell line produces prolactin.
Endocrinology. 1988 Jun; 122(6):2508-17.
Prolactin (PRL) mRNA from human decidua differs from pituitary PRL mRNA but resembles the IM-9-P3 lymphoblast PRL transcript.
Mol Cell Endocrinol. 1989 Jun; 64(1):127-30.
The peripheral hormone level in premenopausal patients with benign breast changes and their modification by various hormone therapies
Gynakologe. 1989 Aug; 22(4):255-61.
Phorbol ester stimulates prolactin release but reduces prolactin mRNA in the human B-lymphoblastoid cell line IM-9-P3.
Mol Cell Endocrinol. 1989 Oct; 66(2):153-61.
Evaluation of endocrine parameters and semen samples: pregnancies following conservative infertility treatment versus IVF therapy.
Hum Reprod. 1989 Nov; 4(8 Suppl):65-72.
Regulation of prolactin secretion in the human B-lymphoblastoid cell line IM-9-P3 by dexamethasone but not other regulators of pituitary prolactin secretion.
Endocrinology. 1989 Dec; 125(6):2853-61.
Patterns of serum-luteinizing hormone surges in stimulated cycles in relation to injections of human chorionic gonadotropin.
Fertil Steril. 1990 Jan; 53(1):69-75.
Clonal derivatives of a human B-lymphoblastoid cell line producing prolactin--a cytogenetic characterization.
Cytotechnology. 1990 Jan; 3(1):43-50.
Morphometric analysis of the endometrium of infertile patients in relation to peripheral hormone levels.
Fertil Steril. 1990 Jul; 54(1):84-9.
Decidual-type prolactin expression by the human myometrium.
Endocrinology. 1991 Jul; 129(1):158-68.
Morphometric characteristics of endometrial biopsies after different types of ovarian stimulation for infertility treatment.
Fertil Steril. 1993 Mar; 59(3):560-6.
Thyroid gland dysfunctions and disorders in pregnancy and puerperium. Prevention, diagnosis and therapy.
Geburtshilfe Frauenheilkd. 1995 Nov; 55(11):M134-6.
Personality markers, physical complaints and microsomal thyroid antibody titer in postpartum women
Z Geburtshilfe Neonatol. 1996 Jul-1996 Aug 31; 200(4):138-43.
Stiffness index identifies patients with osteoporotic fractures better than ultrasound velocity or attenuation alone
Maturitas. 1999 Mar 15; 31(3):221-6.
Continuous, combined hormone replacement: randomized comparison of transdermal and oral preparations.
Obstet Gynecol. 1999 Jul; 94(1):61-5.

